Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury

Short summary

Initiating renal replacement therapy (RRT) early (within 8 hours of diagnosis) in critically ill patients with acute kidney injury (AKI) significantly reduced 90-day all-cause mortality by 15.4% (39.3% vs. 54.7%) compared to delayed initiation (within 12 hours of stage 3 AKI or no initiation).

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