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Redox Biology· 2017Q1· Review

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

Clémence Cheignon, Mireia Tomas, Dominique Bonnefont‐Rousselot, Peter Faller et al.

Short summary

Redox-active metal ions like copper catalyze reactive oxygen species (ROS) production when bound to amyloid-beta (Aβ) peptides, contributing to oxidative damage in Alzheimer's disease (AD).

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Field: Physiology

PhysiologyMedicine