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New England Journal of Medicine· 2016Q1

Osimertinib or Platinum–Pemetrexed in <i>EGFR</i> T790M–Positive Lung Cancer

Tony Mok, Yi‐Long Wu, Myung‐Ju Ahn, Marina Chiara Garassino et al.

Short summary

Osimertinib significantly improved progression-free survival (10.1 vs. 4.4 months) and objective response rate (71% vs. 31%) compared to platinum-pemetrexed in patients with T790M-positive advanced non-small-cell lung cancer who progressed on prior EGFR-TKI therapy.

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Field: Pulmonary and Respiratory Medicine

Pulmonary and Respiratory MedicineMedicine