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Journal of Clinical Oncology· 2013Q1

Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With <i>EGFR</i> Mutations

Lecia V. Sequist, James Chih‐Hsin Yang, Nobuyuki Yamamoto, Kenneth J. O’Byrne et al.

Short summary

Afatinib significantly improved progression-free survival (PFS) by 4.2 months (11.1 vs. 6.9 months) compared to cisplatin plus pemetrexed chemotherapy in patients with advanced lung adenocarcinoma and EGFR mutations.

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Field: Pulmonary and Respiratory Medicine

Pulmonary and Respiratory MedicineMedicine