Pharmaceutics· 2020Q1· Review
Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration
- 1,306citations
- Q1SCImago
- 2020year
Short summary
This review details the complex cellular mechanisms of skin wound healing and highlights emerging technologies like growth factor-activated scaffolds and genetically modified cells for improved regeneration and personalized therapies.
AI-generated from the title and abstract; the full text is not read.
Key points
- Skin wound healing involves complex interactions of cells, growth factors, and cytokines.
- Many chronic wounds heal via repair, not full regeneration, leading to scarring.
- Advanced therapies focus on skin regeneration using scaffolds, growth factors, and bioactive molecules.
- Emerging techniques include genetically modified cells and personalized therapy design.
AI-generated from the title and abstract; the full text is not read.
Abstract
Skin wound healing shows an extraordinary cellular function mechanism, unique in nature and involving the interaction of several cells, growth factors and cytokines. Physiological wound healing restores tissue integrity, but in many cases the process is limited to wound repair. Ongoing studies aim to obtain more effective wound therapies with the intention of reducing inpatient costs, providing long-term relief and effective scar healing. The main goal of this comprehensive review is to focus on the progress in wound medication and how it has evolved over the years. The main complications related to the healing process and the clinical management of chronic wounds are described in the review. Moreover, advanced treatment strategies for skin regeneration and experimental techniques for cellular engineering and skin tissue engineering are addressed. Emerging skin regeneration techniques involving scaffolds activated with growth factors, bioactive molecules and genetically modified cells are exploited to overcome wound healing technology limitations and to implement personalized therapy design.
The authors' abstract, as published at the source. Pharmaceutics, 2020 · DOI ↗
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Field: Rehabilitation
RehabilitationMedicine