Journal of Biomedical Materials Research Part B Applied Biomaterials· 2012Q2· Review
A review of polyvinyl alcohol and its uses in cartilage and orthopedic applications
- 1,098citations
- Q2SCImago
- 2012year
Short summary
Polyvinyl alcohol (PVA) is a biocompatible synthetic polymer suitable for medical implants, with a history of use in orthopedics and potential for cartilage replacement via PVA cryogels.
AI-generated from the title and abstract; the full text is not read.
Key points
- PVA is a synthetic polymer with desirable medical properties including low protein adsorption and biocompatibility.
- It has been used in various medical devices such as contact lenses, eye drops, and embolization particles.
- The review assesses PVA's safety for cartilage replacement, considering historical orthopedic use and biocompatibility studies.
- PVA cryogels are highlighted as a promising material for future cartilage replacement development.
AI-generated from the title and abstract; the full text is not read.
Abstract
Polyvinyl alcohol (PVA) is a synthetic polymer derived from polyvinyl acetate through partial or full hydroxylation. PVA is commonly used in medical devices due to its low protein adsorption characteristics, biocompatibility, high water solubility, and chemical resistance. Some of the most common medical uses of PVA are in soft contact lenses, eye drops, embolization particles, tissue adhesion barriers, and as artificial cartilage and meniscus. The purpose of this review is to evaluate the available published information on PVA with respect to its safety as a medical device implant material for cartilage replacement. The review includes historical clinical use of PVA in orthopedics, and in vitro and in vivo biocompatibility studies. Finally, the safety recommendation involving the further development of PVA cryogels for cartilage replacement is addressed.
The authors' abstract, as published at the source. Journal of Biomedical Materials Research Part B Applied Biomaterials, 2012 · DOI ↗
Continue with a free account
Ask the paper: 3 free questions a day about this paper; save it, get its citation, new summaries every day for your field. Takeaways are Premium.
Continue free on the webSign in with Google or Apple; no card needed. You come back to this paper.
On your phone:
Field: Rheumatology
RheumatologyMedicine