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The Journal of Immunology· 2013Q1

Myeloid-Derived Suppressor Cells Suppress Antitumor Immune Responses through IDO Expression and Correlate with Lymph Node Metastasis in Patients with Breast Cancer

Jinpu Yu, Weijiao Du, Yan Fang, Yue Wang et al.

Short summary

Myeloid-derived suppressor cells (MDSCs) in breast cancer suppress T cell responses via IDO expression, a mechanism dependent on STAT3 phosphorylation and linked to lymph node metastasis.

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Field: Biological Psychiatry

Biological PsychiatryNeuroscience