Annual Review of Entomology· 2012Q1· Review
Odorant Reception in Insects: Roles of Receptors, Binding Proteins, and Degrading Enzymes
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- 2012year
Short summary
Insect olfaction relies on odorant receptors (ORs), odorant-binding proteins (OBPs), and odorant-degrading enzymes (ODEs), with recent research deorphanizing ORs and revealing functions for OBPs and ODEs.
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Key points
- Odorant receptors (ORs) from various insect species have been deorphanized.
- Odorant-binding proteins (OBPs) transport odorants through sensillar lymph.
- Odorant-degrading enzymes (ODEs) may be involved in signal inactivation.
- Drosophila ORs respond to multiple odorants in a combinatorial code.
- Moth ORs show peripheral selectivity for sex pheromones via labeled lines.
AI-generated from the title and abstract; the full text is not read.
Abstract
Our knowledge of the molecular basis of odorant reception in insects has grown exponentially over the past decade. Odorant receptors (ORs) from moths, fruit flies, mosquitoes, and the honey bees have been deorphanized, odorant-degrading enzymes (ODEs) have been isolated, and the functions of odorant-binding proteins (OBPs) have been unveiled. OBPs contribute to the sensitivity of the olfactory system by transporting odorants through the sensillar lymph, but there are competing hypotheses on how they act at the end of the journey. A few ODEs that have been demonstrated to degrade odorants rapidly may act in signal inactivation alone or in combination with other molecular traps. Although ORs in Drosophila melanogaster respond to multiple odorants and seem to work in combinatorial code involving both periphery and antennal lobes, reception of sex pheromones by moth ORs suggests that their labeled lines rely heavily on selectivity at the periphery.
The authors' abstract, as published at the source. Annual Review of Entomology, 2012 · DOI ↗
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