Journal of Neuroscience· 2014Q1

Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury

Jeffrey J. Iliff, Michael Chen, Benjamin A. Plog, Douglas Zeppenfeld et al.

1,152citations
Q1SCImago
2014year

Short summary

Traumatic brain injury (TBI) impairs the brain's waste clearance system (glymphatic pathway) by ~60% for at least a month, leading to tau pathology and neurodegeneration.

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Field: Cellular and Molecular Neuroscience

Cellular and Molecular NeuroscienceNeuroscience