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Nature Communications· 2018Q1

Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

Humberto Mestre, Jeffrey Tithof, Ting Du, Wei Song et al.

Short summary

Cerebrospinal fluid (CSF) flow in brain perivascular spaces (PVSs) is primarily driven by arterial pulsations, with flow speed matching arterial wall motion, suggesting a 'perivascular pumping' mechanism.

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Field: Cellular and Molecular Neuroscience

Cellular and Molecular NeuroscienceNeuroscience