Science· 2012Q1
Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals
- 1,502citations
- Q1SCImago
- 2012year
Short summary
Mammalian circadian clocks exhibit a three-phase transcriptional cycle (poised, activation, repressed) involving CLOCK/BMAL1, with only 22% of cycling mRNAs driven by new transcription, suggesting significant post-transcriptional regulation.
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Endocrine and Autonomic SystemsNeuroscience