Frontiers in Cellular Neuroscience· 2025Q2· Review

Microglia-orchestrated neuroinflammation and synaptic remodeling: roles of pro-inflammatory cytokines and receptors in neurodegeneration

Guang Yang, Xiaolu Xu, Waimao Gao, Xingyu Wang et al.

67citations
Q2SCImago
2025year

Short summary

Overactivated microglia release pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) and engage specific receptors, leading to synaptic alterations and neurodegeneration.

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Field: Neurology (Neuroscience)

NeurologyNeuroscience