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Science Signaling· 2026Q1

ORAI Ca 2+ channels and STIM1 drive capillary-to-arteriole communication in neurovascular coupling

Boris Lavanderos, Alfredo Sanchez Solano, Wanchun Zhu, Pratish Thakore et al.

Short summary

ORAI1 channels and STIM1 are essential for communication from capillaries to arterioles, driving blood flow increases during sustained neuronal activity.

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Field: Sensory Systems

Sensory SystemsNeuroscience