Physiological Reviews· 2015Q1· Review

Store-Operated Calcium Channels

Murali Prakriya, Richard S. Lewis

1,240citations
Q1SCImago
2015year

Short summary

Store-operated calcium channels (SOCs), crucial for cellular functions, are activated by endoplasmic reticulum (ER) calcium depletion, with STIM proteins sensing depletion and Orai proteins forming the channels at ER-plasma membrane junctions.

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Field: Sensory Systems

Sensory SystemsNeuroscience