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Frontiers in Physiology· 2026Q2

Treadmill exercise improves motor deficits and partially normalizes electrophysiological properties of substantia nigra pars reticulata PV-lineage neurons in 6-OHDA-lesioned mice

Wanchun Xue, Jianhua Zhang, Zhiyu Chen

Short summary

Six weeks of treadmill exercise partially improved motor deficits and normalized key electrophysiological properties (input resistance, action potential threshold, firing capacity, adaptation) in substantia nigra pars reticulata (SNr) PV-lineage neurons in 6-OHDA-lesioned mice.

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Field: Developmental Neuroscience

Developmental NeuroscienceNeuroscience