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Accounts of Chemical Research· 2013Q1

Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C–H/Het–H Bond Functionalizations

Lutz Ackermann

Short summary

Ruthenium(II) complexes catalyze alkyne annulations via C-H/heteroatom-H bond cleavage, enabling modular assembly of heterocycles using inexpensive catalysts and acetate assistance for C-H metalation.

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Field: Organic Chemistry

Organic ChemistryChemistry