Organic Letters· 2026Q1
Cu-Catalyzed Cross-Coupling of (Hetero)Aryl Halides with Malonates: One-Pot Assembly of α-Arylacetic Acid Scaffolds
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- Q1SCImago
- 2026year
Short summary
A new one-pot method directly synthesizes α-arylacetic acids from aryl halides and malonates using a Cu/oxalamide catalyst, enabling gram-scale production and late-stage drug modification.
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