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Journal of Agricultural and Food Chemistry· 2026Q1

LC-MS/MS Quantification of Total Milk Protein Allergens: A Dual-Target Approach Using β-Lactoglobulin/β-Casein Standards and Stable Isotope-Labeled Peptide Calibration

Shupeng Yang, Yutong Xu, Ruijie Chen, Siyi Li et al.

Short summary

A new LC-MS/MS method accurately quantifies total milk allergens in processed foods by simultaneously measuring whey (β-lactoglobulin) and casein (β-casein) fractions using specific marker peptides and stable isotope-labeled internal standards.

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Field: Immunology and Allergy

Immunology and AllergyMedicine