Clinical and Translational Allergy· 2013Q1· Review
The skin prick test – European standards
- 896citations
- Q1SCImago
- 2013year
Short summary
European standards for skin prick testing are proposed, defining a positive result as a wheal ≥3 mm diameter after 15-20 minutes and recommending a standard panel of 20 common inhalant allergens.
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Key points
- Skin prick testing is essential for diagnosing IgE-mediated allergies.
- A positive test is defined by a wheal ≥3 mm diameter after 15-20 minutes.
- A standard panel of 20 common European inhalant allergens is proposed.
- Standardization aims to improve diagnostic, clinical, and research comparisons globally.
AI-generated from the title and abstract; the full text is not read.
Abstract
Skin prick testing is an essential test procedure to confirm sensitization in IgE-mediated allergic disease in subjects with rhinoconjunctivitis, asthma, urticaria, anapylaxis, atopic eczema and food and drug allergy. This manuscript reviews the available evidence including Medline and Embase searches, abstracts of international allergy meetings and position papers from the world allergy literature. The recommended method of prick testing includes the appropriate use of specific allergen extracts, positive and negative controls, interpretation of the tests after 15 - 20 minutes of application, with a positive result defined as a wheal ≥3 mm diameter. A standard prick test panel for Europe for inhalants is proposed and includes hazel (Corylus avellana), alder (Alnus incana), birch (Betula alba), plane (Platanus vulgaris), cypress (Cupressus sempervirens), grass mix (Poa pratensis, Dactilis glomerata, Lolium perenne, Phleum pratense, Festuca pratensis, Helictotrichon pretense), Olive (Olea europaea), mugwort (Artemisia vulgaris), ragweed (Ambrosia artemisiifolia), Alternaria alternata (tenuis), Cladosporium herbarum, Aspergillus fumigatus, Parietaria, cat, dog, Dermatophagoides pteronyssinus, Dermatophagoides farinae, and cockroach (Blatella germanica). Standardization of the skin test procedures and standard panels for different geographic locations are encouraged worldwide to permit better comparisons for diagnostic, clinical and research purposes.
The authors' abstract, as published at the source. Clinical and Translational Allergy, 2013 · DOI ↗
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Field: Immunology and Allergy
Immunology and AllergyMedicine