Nutrients· 2016Q1· Review
Quercetin, Inflammation and Immunity
- 1,940citations
- Q1SCImago
- 2016year
Short summary
Quercetin, a plant-derived polyphenol, demonstrates broad anti-inflammatory and immune-modulating effects in vitro and animal models, suggesting potential therapeutic benefits.
AI-generated from the title and abstract; the full text is not read.
Key points
- Quercetin exhibits anti-carcinogenic, anti-inflammatory, and antiviral activities.
- It can attenuate lipid peroxidation, platelet aggregation, and capillary permeability.
- The review covers quercetin's physicochemical properties, dietary sources, and metabolism.
- Evidence suggests beneficial effects on inflammation and immune function.
AI-generated from the title and abstract; the full text is not read.
Abstract
In vitro and some animal models have shown that quercetin, a polyphenol derived from plants, has a wide range of biological actions including anti-carcinogenic, anti-inflammatory and antiviral activities; as well as attenuating lipid peroxidation, platelet aggregation and capillary permeability. This review focuses on the physicochemical properties, dietary sources, absorption, bioavailability and metabolism of quercetin, especially main effects of quercetin on inflammation and immune function. According to the results obtained both in vitro and in vivo, good perspectives have been opened for quercetin. Nevertheless, further studies are needed to better characterize the mechanisms of action underlying the beneficial effects of quercetin on inflammation and immunity.
The authors' abstract, as published at the source. Nutrients, 2016 · DOI ↗
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Field: Biochemistry (Medicine)
BiochemistryMedicine