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Signal Transduction and Targeted Therapy· 2022Q1· Review

Notch signaling pathway: architecture, disease, and therapeutics

Binghan Zhou, Wanling Lin, Yaling Long, Yunkai Yang et al.

Short summary

The Notch signaling pathway, identified over a century ago, plays a dual role in cancer, capable of both promoting and inhibiting tumor development, with its targeted therapies thus far failing to meet expectations.

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Field: Immunology and Allergy

Immunology and AllergyMedicine