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New England Journal of Medicine· 2017Q1

Analysis of Plasma Epstein–Barr Virus DNA to Screen for Nasopharyngeal Cancer

K.C. Allen Chan, John K. S. Woo, Ann D. King, Benny Zee et al.

Short summary

Plasma Epstein-Barr virus (EBV) DNA screening detected early-stage nasopharyngeal carcinoma (NPC) in asymptomatic individuals with 97.1% sensitivity and 98.6% specificity, leading to significantly better 3-year progression-free survival (97% vs. 70%) compared to a historical cohort.

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Field: Otorhinolaryngology

OtorhinolaryngologyMedicine