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Advances in Wound Care· 2013Q1· Review

Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring

Meilang Xue, Chris Jackson

Short summary

Understanding how extracellular matrix (ECM) components reorganize during wound healing is key to developing therapies for preventing hypertrophic and keloid scars.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Extracellular matrix (ECM) components are central to wound healing.
  • Specific ECM reorganization patterns differentiate normal healing from abnormal scarring.
  • Understanding these patterns can guide the development of scar prevention therapies.

AI-generated from the title and abstract; the full text is not read.

Abstract

Better understanding of the exact roles of ECM components in scarring will allow us to produce therapeutic agents to prevent hypertrophic and keloid scars. This review will focus on the components of the ECM and their role in both physiological and pathological (hypertrophic and keloid) cutaneous scar formation.

The authors' abstract, as published at the source. Advances in Wound Care, 2013 · DOI ↗

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Field: Rehabilitation

RehabilitationMedicine