International Journal of Molecular Sciences· 2017Q1

Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing

Mark Hesketh, Katherine B. Sahin, Zoe West, Rachael Z. Murray

877citations
Q1SCImago
2017year

Short summary

Macrophages shift from pro-inflammatory M1 to pro-repair M2 phenotypes during wound healing, with alterations in their number and phenotype dictating scar formation and hindering chronic wound closure.

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Field: Rehabilitation

RehabilitationMedicine