Journal of the Chinese Medical Association· 2017Q3· Review
Wound healing
- 879citations
- Q3SCImago
- 2017year
Short summary
This review synthesizes post-2010 research on wound healing, covering its physiological phases, aberrant outcomes like excessive scarring and chronic wounds, and therapeutic strategies including stem cell therapy and prevention.
AI-generated from the title and abstract; the full text is not read.
Key points
- Normal wound healing progresses through distinct phases: hemostasis/inflammation, proliferation, and remodeling.
- Aberrations in wound healing can lead to excessive scarring (hypertrophic scars, keloids) or chronic wounds (ulcers).
- Research post-2010 has provided insights into the pathogenesis, epidemiology, and in vitro/in vivo studies of excessive wound healing.
- Stem cell therapy and specific prevention strategies are being investigated for managing excessive wound healing.
AI-generated from the title and abstract; the full text is not read.
Abstract
Wound healing is an important physiological process to maintain the integrity of skin after trauma, either by accident or by intent procedure. The normal wound healing involves three successive but overlapping phases, including hemostasis/inflammatory phase, proliferative phase, and remodeling phase. Aberration of wound healing, such as excessive wound healing (hypertrophic scar and keloid) or chronic wound (ulcer) impairs the normal physical function. A large number of sophisticated experimental studies have provided insights into wound healing. This article highlights the information after 2010, and the main text includes (i) wound healing; (ii) wound healing in fetus and adult; (iii) prostaglandins and wound healing; (iv) the pathogenesis of excessive wound healing; (v) the epidemiology of excessive wound healing; (vi) in vitro and in vivo studies for excessive wound healing; (vii) stem cell therapy for excessive wound healing; and (viii) the prevention strategy for excessive wound healing.
The authors' abstract, as published at the source. Journal of the Chinese Medical Association, 2017 · DOI ↗
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Field: Rehabilitation
RehabilitationMedicine