Science· 2013Q1
Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics
- 1,175citations
- Q1SCImago
- 2013year
Short summary
Researchers developed injectable, cellular-scale optoelectronic devices capable of wireless, programmed optogenetic control in freely moving animals.
AI-generated from the title and abstract; the full text is not read.
Key points
- Developed injectable, cellular-scale optoelectronic devices.
- Devices are ultrathin, mechanically compliant, and biocompatible.
- Demonstrated wireless and programmed optogenetic control in freely moving animals.
- Enables complex behavioral control with minimal invasiveness.
AI-generated from the title and abstract; the full text is not read.
Abstract
Successful integration of advanced semiconductor devices with biological systems will accelerate basic scientific discoveries and their translation into clinical technologies. In neuroscience generally, and in optogenetics in particular, the ability to insert light sources, detectors, sensors, and other components into precise locations of the deep brain yields versatile and important capabilities. Here, we introduce an injectable class of cellular-scale optoelectronics that offers such features, with examples of unmatched operational modes in optogenetics, including completely wireless and programmed complex behavioral control over freely moving animals. The ability of these ultrathin, mechanically compliant, biocompatible devices to afford minimally invasive operation in the soft tissues of the mammalian brain foreshadow applications in other organ systems, with potential for broad utility in biomedical science and engineering.
The authors' abstract, as published at the source. Science, 2013 · DOI ↗
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Field: Cellular and Molecular Neuroscience
Cellular and Molecular NeuroscienceNeuroscience