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Science· 2012Q1

A Critical Period for Social Experience–Dependent Oligodendrocyte Maturation and Myelination

Manabu Makinodan, Kenneth M. Rosen, Susumu Ito, Gabriel Corfas

Short summary

Social isolation during a specific post-weaning window in mice impairs prefrontal cortex myelination and cognitive function, with deficits persisting even after social reintroduction.

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Field: Developmental Neuroscience

Developmental NeuroscienceNeuroscience