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Cells· 2019Q1· Review

Oligodendrocytes in Development, Myelin Generation and Beyond

Sarah Kuhn, Laura Gritti, Daniel Crooks, Yvonne Dombrowski

Short summary

Oligodendrocytes, the myelinating cells of the CNS, are generated from adult progenitor cells and are crucial for axonal health, with their pathology linked to diseases like multiple sclerosis and Alzheimer's. Recent findings reveal novel immunomodulatory roles for these cells, though their implications remain unclear.

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Field: Developmental Neuroscience

Developmental NeuroscienceNeuroscience