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Cold Spring Harbor Perspectives in Biology· 2015Q1· Preprint

Oligodendrocyte Development and Plasticity

Dwight E. Bergles, William D. Richardson

Short summary

Oligodendrocytes (OLs) and their precursors (OPCs) exhibit experience-dependent adaptive myelination in the adult CNS, responding to axonal activity to generate more OLs and myelin locally, which is crucial for plasticity and learning like motor learning.

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Field: Developmental Neuroscience

Developmental NeuroscienceNeuroscience