Frontiers in Nutrition· 2018Q1· Review
The Role of Polyphenols in Human Health and Food Systems: A Mini-Review
- 1,276citations
- Q1SCImago
- 2018year
Short summary
Polyphenols show potential protective effects against obesity, neurodegenerative, type 2 diabetes, and cardiovascular diseases, but their bioavailability is affected by food processing, and only a few compounds have officially sanctioned health claims.
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Key points
- Polyphenols are evaluated for protective effects against obesity, neurodegenerative diseases, type 2 diabetes, and cardiovascular diseases.
- Evidence largely stems from animal models, feeding experiments, and human cohort/case-control studies.
- Food processing significantly influences polyphenol bioavailability.
- Only a limited number of specific polyphenolic compounds have officially sanctioned health claims.
- There is a need for increased regulation and guidelines for polyphenol consumption and supplementation.
AI-generated from the title and abstract; the full text is not read.
Abstract
This narrative mini- review summarizes current knowledge of the role of polyphenols in health outcomes-and non-communicable diseases specifically-and discusses the implications of this evidence for public health, and for future directions for public health practice, policy, and research. The publications cited originate mainly from animal models and feeding experiments, as well as human cohort and case-control studies. Hypothesized protective effects of polyphenols in acute and chronic diseases, including obesity, neurodegenerative diseases, type 2 diabetes, and cardiovascular diseases, are evaluated. Potential harmful effects of some polyphenols are also considered, counterbalanced with the limited evidence of harm in the research literature. Recent international governmental regulations are discussed, as the safety and health claims of only a few specific polyphenolic compounds have been officially sanctioned. The implications of food processing on the bioavailability of polyphenols are also assessed, in addition to the health claims and marketing of polyphenols as a functional food. Finally, this mini-review asserts the need for increased regulation and guidelines for polyphenol consumption and supplementation in order to ensure consumers remain safe and informed about polyphenols.
The authors' abstract, as published at the source. Frontiers in Nutrition, 2018 · DOI ↗
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Field: Biochemistry (Medicine)
BiochemistryMedicine