PofoliaShared via Pofolia

Skin Pharmacology and Physiology· 2018

Antioxidant Properties of Ferulic Acid and Its Possible Application

Kamila Zduńska, Agnieszka Dana, Anna Kołodziejczak, Helena Rotsztejn

Short summary

Ferulic acid acts as a potent antioxidant by scavenging free radicals, inhibiting radical-generating enzymes, and boosting scavenger enzyme activity, offering significant photoprotection and anti-aging benefits for skin.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Ferulic acid scavenges free radicals and modulates enzyme activity involved in radical generation and scavenging.
  • It protects key skin structures including keratinocytes, fibroblasts, collagen, and elastin.
  • Ferulic acid inhibits melanogenesis, enhances angiogenesis, and accelerates wound healing.
  • It is used in skincare for photoprotection, delaying photoaging, and skin brightening.
  • The rapid oxidation of ferulic acid limits its practical application.

AI-generated from the title and abstract; the full text is not read.

Abstract

Ferulic acid has low toxicity and possesses many physiological functions (anti-inflammatory, antioxidant, antimicrobial activity, anticancer, and antidiabetic effect). It has been widely used in the pharmaceutical, food, and cosmetics industry. Ferulic acid is a free radical scavenger, but also an inhibitor of enzymes that catalyze free radical generation and an enhancer of scavenger enzyme activity. Ferulic acid has a protective role for the main skin structures: keratinocytes, fibroblasts, collagen, elastin. It inhibits melanogenesis, enhances angiogenesis, and accelerates wound healing. It is widely applied in skin care formulations as a photoprotective agent, delayer of skin photoaging processes, and brightening component. Nonetheless, its use is limited by its tendency to be rapidly oxidized.

The authors' abstract, as published at the source. Skin Pharmacology and Physiology, 2018 · DOI ↗

TakeawaysPremium
Ask the paperFree account

Continue with a free account

Ask the paper: 3 free questions a day about this paper; save it, get its citation, new summaries every day for your field. Takeaways are Premium.

Continue free on the web

Sign in with Google or Apple; no card needed. You come back to this paper.

On your phone:

Field: Biochemistry (Medicine)

BiochemistryMedicine