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Cellular Physiology and Biochemistry· 2013Q3

Skepinone-L, a Novel Potent and Highly Selective Inhibitor of p38 MAP Kinase, Effectively Impairs Platelet Activation and Thrombus Formation

Oliver Borst, Britta Walker, Patrick Münzer, Antonella Russo et al.

Short summary

Skepinone-L, a novel p38 MAP kinase inhibitor, significantly reduced platelet activation and thrombus formation in human platelets by blocking p38 MAPK-dependent synthesis of thromboxane A2.

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Field: Hematology

HematologyMedicine