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Expert Opinion on Drug Delivery· 2012Q1

Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents

Ricardo P. Garay, Raafat El-Gewely, Jonathan K. Armstrong, George Garratty et al.

Short summary

A significant increase in anti-PEG antibodies was observed in healthy blood donors (22-25% occurrence), up from 0.2% two decades prior, suggesting greater exposure to PEG in everyday products.

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Field: Immunology and Allergy

Immunology and AllergyMedicine