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Signal Transduction and Targeted Therapy· 2022Q1· Review

The sirtuin family in health and disease

Qi‐Jun Wu, Tie‐Ning Zhang, Huanhuan Chen, Xuefei Yu et al.

Short summary

Sirtuins (SIRTs), a family of NAD+-dependent deacetylases, regulate key cellular processes like inflammation, metabolism, and apoptosis, making them promising therapeutic targets for diseases including cancer and cardiovascular conditions.

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Field: Geriatrics and Gerontology

Geriatrics and GerontologyMedicine