The Journal of Nutritional Biochemistry· 2013Q1· Review
Benefits of polyphenols on gut microbiota and implications in human health
- 1,564citations
- Q1SCImago
- 2013year
Short summary
Dietary polyphenols significantly influence gut microbiota composition and activity, which in turn modulates polyphenol bioavailability and health effects, forming a crucial two-way interaction.
AI-generated from the title and abstract; the full text is not read.
Key points
- Gut microbiota play a key role in modulating polyphenol production and bioavailability.
- Dietary polyphenols can influence the composition and activity of colonic microbial populations.
- The two-way interaction between polyphenols and the gut microbiota is crucial for health outcomes.
- Research on the impact of polyphenols on human gut microbiota is limited, often focusing on single compounds.
AI-generated from the title and abstract; the full text is not read.
Abstract
The biological properties of dietary polyphenols are greatly dependent on their bioavailability that, in turn, is largely influenced by their degree of polymerization. The gut microbiota play a key role in modulating the production, bioavailability and, thus, the biological activities of phenolic metabolites, particularly after the intake of food containing high-molecular-weight polyphenols. In addition, evidence is emerging on the activity of dietary polyphenols on the modulation of the colonic microbial population composition or activity. However, although the great range of health-promoting activities of dietary polyphenols has been widely investigated, their effect on the modulation of the gut ecology and the two-way relationship "polyphenols ↔ microbiota" are still poorly understood. Only a few studies have examined the impact of dietary polyphenols on the human gut microbiota, and most were focused on single polyphenol molecules and selected bacterial populations. This review focuses on the reciprocal interactions between the gut microbiota and polyphenols, the mechanisms of action and the consequences of these interactions on human health.
The authors' abstract, as published at the source. The Journal of Nutritional Biochemistry, 2013 · DOI ↗
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Field: Pathology and Forensic Medicine
Pathology and Forensic MedicineMedicine